Blar i forfatter "Heymann, Dominique"

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    • Circulating tumor cell-derived pre-clinical models for personalized medicine 

      Tellez Gabriel, Marta; Cochonneau, Denis; Jubelin, Camille; Heymann, Marie-Françoise; Heymann, Dominique (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-24)
      The main cause of death from cancer is associated with the development of metastases, resulting from the inability of current therapies to cure patients at metastatic stages. Generating preclinical models to better characterize the evolution of the disease is thus of utmost importance, in order to implement effective new cancer biomarkers and therapies. Circulating Tumor Cells (CTCs) are good ...

    • Circulating tumor cells as a tool for assessing tumor heterogeneity 

      Tellez Gabriel, Marta; Heymann, Marie-Françoise; Heymann, Dominique (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-19)
      Tumor heterogeneity is the major cause of failure in cancer prognosis and prediction. Accurately detecting heterogeneity for the development of biomarkers and the detection of the clones resistant to therapy is one of the main goals of contemporary medicine. Metastases belong to the natural history of cancer. The present review gives an overview on the origin of tumor heterogeneity. Recent progress ...